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Potential Benefits of Orally-Ingested Aloe Juice
Written by Administrator
Friday, 23 March 2007
Potential Benefits of Orally-Ingested Aloe Juice (Note:
Organic aloe vera is a key component in Body Balance, by Life Force)
Scientific evidence is accruing in both animal and human studies
which suggest increasing credibility for the benefits of ingested
aloe juice for a number of conditions:
1. Cardiovascular System.
A. Aloe constituents include a salt, calcium isocitrate, which in
animal studies possesses actions similar to digitalis (26) and increases
the force of cardiac contraction. B. Other constituents have been
found to lower the cholesterol level (10,11) as well as the triglyceride
level (4, 10, 16). A large clinical study suggested that extant
atheromatous cardiovascular disease could be reversed by the ingestion
of aloe (1).
2. Gastrointestinal System.
A. Gastrointestinal ulcers showed accelerated healing rates (11)
in animal models, and pretreatment with aloe prior to inducing ulcers
in animal models suggested a high degree of ulcer protection (19).
The triterpene, lupeol, documented as an aloe constituent has been
implicated as a possible ulcer protective agent (12, 23). An uncontrolled
human study in which the aloe/petrolatum material was ingested was
interpreted by the authors as ulcer protective (3). B. Evidence
has been gathered in animals in which experimental cirrhosis of
the liver was induced suggesting that the administration of aloe
provided protection of the liver cells against the cirrhosis-inducing
agents (20, 22).
3. Skeletal System.
A. The most prevalent use of orally-ingested aloe beverages anecdotally
has been for arthritis and other inflammatory conditions, experimental
evidence corroborating anti-inflammatory activity of several aloe
constituents in various animal models cab be found reported in the
scientific literature (5, 6, 7, 8, 9 15, 24, 25).B. Acceleration
of incorporation of calcium and phosphorus in callus formation in
sites of experimental bone fractures has been demonstrated in animal
models (17, 21).
4. Endocrine System.
Studies in both type 1 and type 2 diabetes mellitus in animal models
reflect hypoglycemic activity of various aloe constituents (2, 13,
14). Other investigations suggest that aloe may contain constituents
which have the capability of stimulating regeneration of cells in
the islets of langerhans including the beta cells, the site of insulin
synthesis and release (18). Recently published studies in humans
given aloe preparations showed significant, long-lasting blood glucose
control properties (4, 27).
References
1. AGARWAL GP:
Prevention of athermanous heart disease. Angelology 36: 485-492,
1985.
2. AL-AWADI FM, GUMAN KA:
Studies on the activity of individual plants of an anti-diabetic
plant mixture. Acta Diabetol Lat 24:37-42, 1987.
3. BLITZ JJ, SMITH JW, GERARD JR:
Aloe Vera Gel in peptic ulcer therapy, preliminary report, J Am
Osteopath Assoc 62:731-735, 1963.
4. BUNYAPRAPHATSARA N, YONGCHAIYUDHA S, RUNGPITARANGSI V, CHOKECHAIJAROENPORN
O,
Anti diabetic activity of Aloe Vera L. juice II. Clinical trial
in diabetes mellitus patients in combination with glibenclamide.
Phytomed 3:245-248, 1996.
5. DAVIS RH, DONATO JJ, HARTMAN GM, HAAS RC:
Anti-inflammatory and wound healing activity of a growth abstained
in Aloe Vera. J Am Podiatr Med Assoc 84:77-81, 1994.
6. DAVIS RH, LEITNER MG, RUSSO JM:
Topical anti-inflammatory activity of Aloe Vera as measured by ear
swelling. J Am Podiatr Med Assoc 77:610-612, 1987.
7. DAVIS RH, LEITNER MG, RUSSO JM, BYRNE ME:
Anti-inflammatory activity of Aloe Vera against a spectrum of irritants.
J Am Podiatr Med Assoc 79:263-276, 1989.
8. DAVIS RH, ROSENTHAL KY, CESARIO LR, ROUW GA:
Processed Aloe Vera administered topically inhibits inflammation.
J Am Podiatr Med Assoc 79:395-397,1989.
9. DAVIS RH, STEWART GJ, BREGMAN PJ:
Aloe Vera and the inflamed synovial pouch model. J Am Podiatr Med
Assoc 82:140-148, 1992.
10. DIXIT VP, JOSHI S:
Effect of Aloe Barbadensis and clofibrate on serum lipids in Triniton-induced
hyperlipidemia in Presbyter Entellus Entellus Monkeys, Indian J
Med Res 78:417-421, 1983.
11. GALAL EE, KANDIL A, HEGAZY E, EL GHOROURY M, GOBRAN W:
Aloe Vera and gastrointestinal ulceration, J Drug Res Egypt 7:73-77,
1975.
12. GUPTA MB, NATH R, GUPTA GP, BHARGAVA KP:
Anti ulcer activity of some plant triterpenoids, Indian J Med Res
73:649-652, 1981.
13. HIKINO H, HAYASHI T:
Hypoglycemic polysaccharides extraction from Aloe species, Jpn Kokai
Tokkyo Koho, JP 60,214,741, 28 Oct 1985.
14. HIKINO H, TAKAHASHI M, MURAKAMI M, KONNO C, MIRIN Y, KARIKURA
M, HAYASHI T:
Isolation and hypoglycemic activity of arborans A and B, glycans
of Aloe arborescence var, natalensis leaves, Int J Crude Drug Res
24:183-186, 1986.
15. HUTTER JA, SALMAN M, STAVINOHA WB, SATSANGI N, WILLIAMS RF,
STREEPER RT, WEINTRAUB ST:
Anti-inflammatory C-glucosyl chromone from Aloe barbadensis, J Natural
Prod 59:541-543, 1996.
16. JOSHI S. DIXIT VP:
Hypolipidemia effect of Aloe barbadensis (Aloe fraction I) in cholesterol-fed
rats. I. Lipid and lipoprotein metabolism, Proc Nat Acad Sci India,
Sect B (Biol Sci) 56:339-342, 1986.
17. KADYROV MA, SHARKIROV DSH:
treatment of fractures by adaptogens under experimental conditions.
Eksp Khu Anesteziol 12:50-52, 1967.
18. KALINICHEVA NV, SHAPKINA AV:
Stimulation of the regeneration of the insular epithelium of the
pancreas by some drugs. Tr Leningr Sanit-Gig Med Inst 112:58-64,
1976.
19. KANDIL A, GOBRAN W:
Protection of gastric mucosa by Aloe Vera, J Drug Res Egypt 11:191-196,
1979.
20. SAVITSKII VI:
The effect of tissue preparations on the biochemical processes of
the body, In: The use of tissue preparations in animal husbandry
and veterinary medicine, Urozhai, Kiev ():31-41,1966. From: Ref
Zh Otd Vyp Farmakol Khimioter Sredstva Toksikol, No. 6, 54638, 1967.
21. SHAMATOV NM:
Effect of Aloe extract on the accumulation of Clcium45 and Phosphorus32
in normal and calloused bones, Uckenye Zapiski 2-01 Moskov Med Inst
6:67-69, 1957. Ref. Zh Khim, Biol Khim, 1959, Abstract #3313.
22. SOLOV'EVA VP:
Effect of Aloe extract on some biochemical indicators of normal
and sick persons. Vrachebnoe Delo ():93-98, 1958.
23. SUGA T, HIRATA T:
The efficacy of the Aloe plants chemical constituents and biological
activities. Cosmet & Toil 98:105-108, 1983.
24. VAZQUEZ B, AVILA G, SEGURA D, ESCALANTE B:
Anti-inflammatory activity of extracts from Aloe Vera Gel. J Ethnopharmacol
55:69-75, 1996.
25. YAGI A, HARADA N, SHIMOMURA K, NISHIOKA I:
Bradykinin-Degradin glycoprotein in Aloe arborescens var. Natalensis.
Planta Med 53:19-21, 1987.
26. YAGI A, SHIBATA S, NISHIOKA I, IWADARE S, ISHIDA Y:
Cardiac stimulant action of constituents of Aloe saponaria. J Pharm
Sci 71:739-741, 1982.
27. YONGCHAIYUDHA S, RUNGPITARANGSI V, BUNYAPRAPHATSARA N, CHOKECHAIJAROENPORN
0:
Anti diabetic activity of Aloe Vera L. Juice I. Clinical trial in
new cases of diabetes mellitus. Phytomed 3:241-243, 1996.
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